Recombinant Human KIRREL3 Protein, MYC/DDK-tagged

• Cat.No.: KIRREL3-554H
• Product Overview: Recombinant human KIRREL3 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 85.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: kirre like nephrin family adhesion molecule 3[ Homo sapiens ]
• Official Symbol: KIRREL3
• Synonyms: KIRRE; MRD4; NEPH2; PRO4502
• Gene ID: 84623
• mRNA Refseq: NM_001161707.1
• Protein Refseq: NP_001155179.1
• MIM: 607761
• UniProt ID: Q8IZU9