Recombinant Human KLB Protein, His tagged

• Cat.No.: KLB-14H
• Product Overview: Klotho beta Protein, Human (968a.a, HEK293, His) is the recombinant human-derived Klotho beta protein, expressed by HEK293, with C-His tag.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 30-997 aa
• Description: Enables fibroblast growth factor binding activity and fibroblast growth factor receptor binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to act upstream of or within positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to be located in plasma membrane.
• Form: Lyophilized powder
• Molecular Mass: 112.9 kDa
• Endotoxin: <1 EU/μg by LAL
• Purity: > 90% by SDS-PAGE
• Storage: Stored at -20 centigrade for 2 years. After reconstitution, it is stable at 4 centigrade for 1 week or -20 centigrade for longer (with carrier protein). It is recommended to freeze aliquots at -20 or -80 centigrade for extended storage.
• Shipping: Room temperature in continental US; may vary elsewhere.
• Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
• Storage Buffer: Lyophilized from 0.22 μm filtered solution of PBS, pH7.4 with trehalose as protectant.

Gene Information

• Gene Name: KLB klotho beta [ Homo sapiens (human) ]
• Official Symbol: KLB
• Synonyms: KLB; klotho beta; BKL; beta-klotho; b-Klotho; betaKlotho; klotho beta like; klotho beta-like protein
• Gene ID: 152831
• mRNA Refseq: NM_175737
• Protein Refseq: NP_783864
• MIM: 611135
• UniProt ID: Q86Z14