Recombinant Human KLK11 protein, His & T7-tagged

• Cat.No.: KLK11-753H
• Product Overview: Recombinant Human KLK11 aa. (Ile39~Asn282 (Accession # Q9UBX7)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 30.5kDa
• Protein length: Ile39~Asn282 (Accession # Q9UBX7)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: KLK11 kallikrein related peptidase 11 [ Homo sapiens (human) ]
• Official Symbol: KLK11
• Synonyms: TLSP; PRSS20; hK11; hippostasin; serine protease 20; trypsin-like protease; kallikrein-11
• Gene ID: 11012
• mRNA Refseq: NM_001136032.2
• Protein Refseq: NP_001129504.1
• UniProt ID: Q9UBX7