Recombinant Human KLK6 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | KLK6-1551H |
Product Overview : | KLK6 MS Standard C13 and N15-labeled recombinant protein (NP_001012983) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 26.86 kDa |
AA Sequence : | MKKLMVVLSLIAAAWAEEQNKLVHG GPCDKTSHPYQAALYTSGHLLCGGV LIHPLWVLTAAHCKKPNLQVFLGKH NLRQRESSQEQSSVVRAVIHPDYDA ASHDQDIMLLRLARPAKLSELIQPL PLERDCSANTTSCHILGWGKTADGD FPDTIQCAYIHLVSREECEHAYPGQ ITQNMLCAGDEKYGKDSCQGDSGGP LVCGDHLRGLVSWGNIPCGSKEKPG VYTNVCRYTNWIQKTIQAKTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | KLK6 kallikrein-related peptidase 6 [ Homo sapiens (human) ] |
Official Symbol : | KLK6 |
Synonyms : | KLK6; kallikrein-related peptidase 6; kallikrein 6 (neurosin, zyme), protease, serine, 18, PRSS9, PRSS18; kallikrein-6; Bssp; Klk7; neurosin; zyme; protease M; serine protease 9; serine protease 18; hK6; SP59; PRSS9; PRSS18; MGC9355; |
Gene ID : | 5653 |
mRNA Refseq : | NM_001012965 |
Protein Refseq : | NP_001012983 |
MIM : | 602652 |
UniProt ID : | Q92876 |
Products Types
◆ Recombinant Protein | ||
KLK6-1040H | Recombinant Human KLK6 protein(Met1-Lys244) | +Inquiry |
KLK6-690H | Recombinant Human KLK6 Protein, MYC/DDK-tagged | +Inquiry |
KLK6-4932H | Recombinant Human KLK6 Protein, GST-tagged | +Inquiry |
KLK6-2255R | Recombinant Rhesus Macaque KLK6 Protein, His (Fc)-Avi-tagged | +Inquiry |
KLK6-3235H | Recombinant Human KLK6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
KLK6-1559HCL | Recombinant Human KLK6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (6)
Ask a questionStudies have shown that Klk6 recombinant protein may be involved in the occurrence and progression of tumors, especially in pancreatic and gastric cancers.
The level of Klk6 recombinant protein in pregnant women may change due to the needs of fetal growth and development, and regular monitoring is required.
The current treatments for Klk6 recombinant protein mainly include gene therapy, protein replacement therapy, and drug therapy for trypsin activity.
Studies have shown that Klk6 recombinant protein may be associated with cardiovascular diseases, liver diseases, and lung diseases.
Klk6 recombinant protein is mainly involved in the digestive process in the human body, helping to break down proteins in food.
If the level of Klk6 recombinant protein is abnormal, the treatment may include the use of drugs or other special treatments, depending on the condition and the doctor's recommendation.
Customer Reviews (3)
Write a reviewWhen experimenting with the KLK6, clear and consistent results are available for easy data analysis and interpretation.
KLKKLK6 products are available in a wide range of specifications for experimental designs of different sizes and needs.
KLK6 has a long half-life and is able to maintain stability and reliability during experiments.
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