Recombinant Human KMT2A Complex, His-tagged
Cat.No. : | KMT2A-128H |
Product Overview : | Recombinant Human MLL1(3745-3969), WDR5(22-334), RbBP5(1-538), Ash2L(2-534), DPY-30(1-99) protein, fused with N-terminal His-tag on all subunits, was expressed in E.coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 3745-3969;22-334;1-538;2-534;1-99 a.a. |
Form : | 20 mM Tris-HCl, pH 7.5, 300 mM NaCl, 1 mM TCEP (tris(2-carboxyethyl)phosphine HCl), 10% (w/v) glycerol, 1 µM ZnCl2. |
Molecular Mass : | 212.0 kDa |
Purity : | >90% by SDS-PAGE |
Storage : | Store at -80°C. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles. |
Gene Name | KMT2A lysine (K)-specific methyltransferase 2A [ Homo sapiens ] |
Official Symbol | KMT2A |
Synonyms | HRX; MLL; MLL1; TRX1; ALL-1; CXXC7; HTRX1; MLL1A; WDSTS; MLL-AF9; MLL/GAS7; TET1-MLL; CDK6/MLL fusion protein; CXXC-type zinc finger protein 7; MLL-AF4 der(11) fusion protein; MLL/ENL fusion protein; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; lysine N-methyltransferase 2A; mixed lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); rearranged MLL protein; trithorax-like protein; zinc finger protein HRX |
Gene ID | 4297 |
mRNA Refseq | NM_001197104 |
Protein Refseq | NP_001184033 |
MIM | 159555 |
UniProt ID | Q03164 |
Chromosome Location | 11q23 |
Pathway | Chromatin modifying enzymes, organism-specific biosystem; Chromatin organization, organism-specific biosystem; Lysine degradation, conserved biosystem |
Function | AT DNA binding; chromatin binding; core promoter sequence-specific DNA binding |
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Not For Human Consumption!
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