Recombinant Human KMT2A Protein KMT2A-002H

Recombinant Human KMT2A Protein

PRODUCTS

Home / Products / Recombinant Human KMT2A Protein

Recombinant Human KMT2A Protein

KMT2A Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : KMT2A-002H
Product Overview : Recombinant Human KMT2A protein without tag was expressed in E.coli
Description : This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Molecular Mass : 200.1 kDa
Purity : ≥90% estimated by SDS-PAGE
Stability : ≥ 6 months
Storage : -80 centigrade
Shipping : Dry ice in continental US, may vary elsewhere.
Gene Name : KMT2A lysine methyltransferase 2A [ Homo sapiens (human) ]
Official Symbol : KMT2A
Synonyms : KMT2A; lysine methyltransferase 2A; HRX; MLL; MLL1; TRX1; ALL-1; CXXC7; HTRX1; MLL1A; WDSTS; histone-lysine N methyltransferase 2A; CXXC-type zinc finger protein 7; lysine (K)-specific methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); trithorax-like protein; zinc finger protein HRX; EC 2.1.1.354
Gene ID : 4297
mRNA Refseq : NM_005933
Protein Refseq : NP_005924
MIM : 159555
UniProt ID : Q03164

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy