Recombinant Human KREMEN1 Protein, MYC/DDK-tagged

• Cat.No.: KREMEN1-889H
• Product Overview: Recombinant human KREMEN1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 48.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: kringle containing transmembrane protein 1[ Homo sapiens ]
• Official Symbol: KREMEN1
• Synonyms: FLJ31863; KREMEM1; KREMEN; KRM1; KREMEM1; KREMEN; KRM1; OTTHUMP00000028977; kringle-coding gene marking the eye and the nose; kringle-containing transmembrane protein 1; kringle containing transmembrane protein 1
• Gene ID: 83999
• mRNA Refseq: NM_001039570.2
• Protein Refseq: NP_001034660
• MIM: 609898
• UniProt ID: Q96MU8