Recombinant Human L1CAM Protein, Fc/His-tagged, Alexa Fluor 555 conjugated

Cat.No. : L1CAM-628HAF555
Product Overview : Alexa Fluor 555 conjugated recombinant human L1CAM precursor extracellular domain (NP_000416.1) (Met 1-Glu 1120), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell.
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Source : HEK293
Species : Human
Tag : Fc/His
Form : Lyophilized
Molecular Mass : The recombinant human CD171/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 1348 amino acids and predicts a molecular mass of 151 kDa. As a result of glycosylation, the rh L1CAM/Fc monomer migrates as approximately 220-240 kDa band in SDS-PAGE under reducing conditions.
Protein length : 1348
Endotoxin : < 1.0 EU/ μg of the protein as determined by the LAL method.
Characteristic : Disulfide-linked homodimer
Labeled with Alexa Fluor 555 via amines
With an excitation and emission maximum of 555/565 nm, Alexa Fluor 555 can be efficiently excited using a 543 nm He-Ne laser line and detected under standard TRITC/Cy3 filters.
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH 7.4
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : L1CAM L1 cell adhesion molecule [ Homo sapiens ]
Official Symbol : L1CAM
Gene ID : 3897
mRNA Refseq : NM_000425
Protein Refseq : NP_000416
MIM : 308840
UniProt ID : P32004

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any L1CAM-targeted therapies in clinical trials? 08/03/2022

Some clinical trials are exploring L1CAM-targeted therapies in the context of cancer treatment.

Can L1CAM be used as a diagnostic marker for neurological disorders? 11/21/2019

L1CAM mutations can be diagnosed through genetic testing, aiding in the diagnosis of L1 syndrome and related conditions.

Can L1CAM be a therapeutic target in cancer treatment? 07/03/2019

L1CAM has been explored as a potential therapeutic target for inhibiting tumor metastasis in some cancer types.

Are there clinical applications for L1CAM in neurodegenerative diseases? 02/05/2018

L1CAM is not typically associated with neurodegenerative diseases, but its role in neural development may have implications for regenerative medicine.

In what other medical conditions is L1CAM implicated? 10/30/2017

L1CAM has been associated with certain developmental disorders and cognitive deficits in addition to cancer and neurological disorders.

Customer Reviews (3)

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Reviews
04/11/2020

    L1CAM protein is an enzyme involved in the digestion of carbohydrates, specifically starch.

    07/07/2019

      A reliable manufacturer ensures the production and purification of L1CAM protein, maintaining its quality and purity.

      10/08/2017

        Manufacturers should provide detailed information about the production process, quality control measures, and purity assessment methods employed.

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