| Description : |
The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). |
| Source : |
HEK293 |
| Species : |
Human |
| Form : |
Lyophilized |
| Molecular Mass : |
52.8 kDa |
| Protein Length : |
481 |
| AA Sequence : |
MGALARALPSILLALLLTSTPEALG ANPGLVARITDKGLQYAAQEGLLAL QSELLRITLPDFTGDLRIPHVGRGR YEFHSLNIHSCELLHSALRPVPGQG LSLSISDSSIRVQGRWKVRKSFFKL QGSFDVSVKGISISVNLLLGSESSG RPTVTASSCSSDIADVEVDMSGDLG WLLNLFHNQIESKFQKVLESRICEM IQKSVSSDLQPYLQTLPVTTEIDSF ADIDYSLVEAPRATAQMLEVMFKGE IFHRNHRSPVTLLAAVMSLPEEHNK MVYFAISDYVFNTASLVYHEEGYLN FSITDDMIPPDSNIRLTTKSFRPFV PRLARLYPNMNLELQGSVPSAPLLN FSPGNLSVDPYMEIDAFVLLPSSSK EPVFRLSVATNVSATLTFNTSKITG FLKPGKVKVELKESKVGLFNAELLE ALLNYYILNTFYPKFNDKLAEGFPL PLLKRVQLYDLGLQIHKDFLFLGAN VQYMRV |
| Purity : |
> 98% |
| Applications : |
Migration Assay; |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
