Recombinant Human LCMT2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human LCMT2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : LCMT2-6269H
Product Overview : LCMT2 MS Standard C13 and N15-labeled recombinant protein (NP_055608) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW).
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 75.6 kDa
AA Sequence : MGPRSRERRA GAVQNTNDSS ALSKRSLAAR GYVQDPFAAL LVPGAARRAP LIHRGYYVRA RAVRHCVRAF LEQIGAPQAA LRAQILSLGA GFDSLYFRLK TAGRLARAAV WEVDFPDVAR RKAERIGETP ELCALTGPFE RGEPASALCF ESADYCILGL DLRQLQRVEE ALGAAGLDAA SPTLLLAEAV LTYLEPESAA ALIAWAAQRF PNALFVVYEQ MRPQDAFGQF MLQHFRQLNS PLHGLERFPD VEAQRRRFLQ AGWTACGAVD MNEFYHCFLP AEERRRVENI EPFDEFEEWH LKCAHYFILA ASRGDTLSHT LVFPSSEAFP RVNPASPSGV FPASVVSSEG QVPNLKRYGH ASVFLSPDVI LSAGGFGEQE GRHCRVSQFH LLSRDCDSEW KGSQIGSCGT GVQWDGRLYH TMTRLSESRV LVLGGRLSPV SPALGVLQLH FFKSEDNNTE DLKVTITKAG RKDDSTLCCW RHSTTEVSCQ NQEYLFVYGG RSVVEPVLSD WHFLHVGTMA WVRIPVEGEV PEARHSHSAC TWQGGALIAG GLGASEEPLN SVLFLRPISC GFLWESVDIQ PPITPRYSHT AHVLNGKLLL VGGIWIHSSS FPGVTVINLT TGLSSEYQID TTYVPWPLML HNHTSILLPE EQQLLLLGGG GNCFSFGTYF NPHTVTLDLS SLSAGQTRTR PLEQKLISEE DLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : LCMT2 leucine carboxyl methyltransferase 2 [ Homo sapiens (human) ]
Official Symbol : LCMT2
Synonyms : LCMT2; leucine carboxyl methyltransferase 2; KIAA0547; MGC9534; PPM2; tRNA yW synthesizing protein 4; TYW4; tRNA-yW synthesizing protein 4; tRNA-Wybutosine-synthesizing protein 4; p21WAF1/CIP1 promoter-interacting protein; FLJ51321;
Gene ID : 9836
mRNA Refseq : NM_014793
Protein Refseq : NP_055608
MIM : 611246
UniProt ID : O60294

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