Recombinant Human LDLR protein, His-tagged, Biotinylated
|Product Overview :
|Biotinylated Recombinant Human LDLR protein(NP_000518.1)(Met1-Arg788), fused with His tag, was expressed in HEK293.
- Gene Information
- Related Products
|Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
|Molecular Mass :
|The recombinant human LDLR consists of 777 amino acids and predicts a molecular mass of 86 kDa.
|Protein Length :
|< 1.0 EU per μg protein as determined by the LAL method.
|> 85 % as determined by SDS-PAGE
|Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
|Gene Name :
|LDLR low density lipoprotein receptor [ Homo sapiens ]
|Official Symbol :
|LDLR; low density lipoprotein receptor; low-density lipoprotein receptor; familial hypercholesterolemia; LDL receptor; low-density lipoprotein receptor class A domain-containing protein 3; FH; FHC; LDLCQ2;
|Gene ID :
|mRNA Refseq :
|Protein Refseq :
|UniProt ID :
|◆ Recombinant Protein
|Recombinant Human LDLR Protein, Fc-tagged
|Recombinant Human LDLR Protein, MYC/DDK-tagged
|Recombinant Mouse Ldlr Protein, His (Fc)-Avi-tagged
|Recombinant Human LDLR Protein, His-tagged
|Active Recombinant Human LDLR Protein, His-Avi-tagged, Biotinylated
|◆ Native Protein
|Native Human Lipoprotein
|Recombinant Human LDLR cell lysate
|Recombinant Mouse LDLR cell lysate
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (5)Ask a question
Yes, conditions where increasing the expression or function of LDLR could potentially aid in reducing circulating LDL cholesterol and minimizing cardiovascular risk.
Yes, research is continually conducted to better understand LDLR-related conditions and to develop more effective treatments, including gene-editing technologies and novel therapies.
Dysfunction in LDLR can lead to high levels of LDL cholesterol in the blood, contributing to conditions like familial hypercholesterolemia and an increased risk of heart disease.
A dysfunctional LDLR can lead to an accumulation of LDL cholesterol in the arteries, promoting atherosclerosis, the hardening and narrowing of arteries.
Treatments involve lifestyle changes, cholesterol-lowering medications, and in some cases, gene therapies or specialized medications targeting the LDL receptor.
Customer Reviews (3)Write a review
The LDLR protein stands out for its exceptional quality, making it an excellent choice to meet my experimental requirements.
Its purity and consistency guarantee reliable and reproducible results, ensuring the reliability of my research outcomes.
the LDLR protein offers superior quality and reliability, making it a perfect fit for my experimental needs.
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