Recombinant Human LDOC1 protein, His & T7-tagged

• Cat.No.: LDOC1-7888H
• Product Overview: Recombinant Human LDOC1 aa. (Met1~Tyr146 (Accession # O95751)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 20.7kDa.
• Protein length: Met1~Tyr146 (Accession # O95751)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 4.1.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: LDOC1 LDOC1, regulator of NFKB signaling [ Homo sapiens (human) ]
• Official Symbol: LDOC1
• Synonyms: LDOC1; LDOC1, regulator of NFKB signaling; Mar7; RTL7; BCUR1; Mart7; SIRH7; protein LDOC1; Sushi-Ichi retrotransposon homolog 7; breast cancer, up-regulated 1; leucine zipper down-regulated in cancer 1; leucine zipper downregulated in cancer; leucine zipper protein down-regulated in cancer cells; mammalian retrotransposon-derived 7; retrotransposon Gag like 7
• Gene ID: 23641
• mRNA Refseq: NM_012317.3
• Protein Refseq: NP_036449.1
• UniProt ID: O95751