Recombinant Human LEO1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LEO1-5824H
• Product Overview: LEO1 MS Standard C13 and N15-labeled recombinant protein (NP_620147) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: LEO1, parafibromin (CDC73), CTR9, and PAF1 form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 75.4 kDa
• AA Sequence: MADMEDLFGSDADSEAERKDSDSGS DSDSDQENAASGSNASGSESDQDER GDSGQPSNKELFGDDSEDEGASHHS GSDNHSERSDNRSEASERSDHEDND PSDVDQHSGSEAPNDDEDEGHRSDG GSHHSEAEGSEKAHSDDEKWGREDK SDQSDDEKIQNSDDEERAQGSDEDK LQNSDDDEKMQNTDDEERPQLSDDE RQQLSEEEKANSDDERPVASDNDDE KQNSDDEEQPQLSDEEKMQNSDDER PQASDEEHRHSDDEEEQDHKSESAR GSDSEDEVLRMKRKNAIASDSEADS DTEVPKDNSGTMDLFGGADDISSGS DGEDKPPTPGQPVDENGLPQDQQEE EPIPETRIEVEIPKVNTDLGNDLYF VKLPNFLSVEPRPFDPQYYEDEFED EEMLDEEGRTRLKLKVENTIRWRIR RDEEGNEIKESNARIVKWSDGSMSL HLGNEVFDVYKAPLQGDHNHLFIRQ GTGLQGQAVFKTKLTFRPHSTDSAT HRKMTLSLADRCSKTQKIRILPMAG RDPECQRTEMIKKEEERLRASIRRE SQQRRMREKQHQRGLSASYLEPDRY DEEEEGEESISLAAIKNRYKGGIRE ERARIYSSDSDEGSEEDKAQRLLKA KKLTSDEEGEPSGKRKAEDDDKANK KHKKYVISDEEEEDDDTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component [ Homo sapiens (human) ]
• Official Symbol: LEO1
• Synonyms: LEO1; Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); RNA polymerase-associated protein LEO1; replicative senescence down-regulated leo1-like protein; RDL
• Gene ID: 123169
• mRNA Refseq: NM_138792
• Protein Refseq: NP_620147
• MIM: 610507
• UniProt ID: Q8WVC0