Recombinant Human LFNG Protein (1-250 aa), GST-tagged

• Cat.No.: LFNG-2140H
• Product Overview: Recombinant Human LFNG Protein (1-250 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Neuroscience. Protein Description: Full Length of Isoform 2.

Specification

• Description: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 55.2 kDa
• Protein length: 1-250 aa
• AA Sequence: MTPGRCCLAADIQVETFIFTDGEDE ALARHTGNVVITNCSAAHSRQALSC KMAVEYDRFIESGRKWFCHVDDDNY VNLRALLRLLASYPHTRDVYVGKPS LDRPIQAMERVSENKVRPVHFWFAT GGAGFCISRGLALKMSPWASGGHFM NTAERIRLPDDCTIGYIVEALLGVP LIRSGLFHSHLENLQQVPTSELHEQ VTLSYGMFENKRNAVHVKGPFSVEA DPSRFRSIHCHLYPDTPWCPRTAIF
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [ Homo sapiens ]
• Official Symbol: LFNG
• Synonyms: LFNG; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; SCDO3
• Gene ID: 3955
• mRNA Refseq: NM_001040167
• Protein Refseq: NP_001035257
• MIM: 602576
• UniProt ID: Q8NES3