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Recombinant Human LGALS12 Protein (Ser2-Ser336), N-His tagged, Animal-free, Carrier-free

Cat.No. : LGALS12-301H
Product Overview : Recombinant Human LGALS12 Protein (Ser2-Ser336) with N-His tag was expressed in E. coli and Animal-free as well as Carrier-free.
  • Specification
  • Gene Information
  • Related Products
Description : Galectin-12 (Gal-12) is a lectin family member and is one of the tandem repeat-type galectins containing two carbohydrate recognition domains (CRD) connected by a linker region in a single peptide chain. The CRD is responsible for β-galactoside binding and is required to interact with the VPS13C protein. It has been reported that galectin-12 is presented in the adipose tissue but also expressed in macrophages and other leukocytes. Galectin-12 participates in many biological activities including cell cycle regulation, apoptosis, and cell differentiation. Moreover, galectin-12 has emerged as a crucial factor in driving the macrophage to M1 polarization, leading to inflammation and reducing insulin sensitivity in adipocytes.
Source : E. coli
Species : Human
Tag : N-His
Form : Lyophilized
Molecular Mass : The protein has a calculated MW of 38.4 kDa.
The protein migrates as 38 kDa under reducing condition (SDS-PAGE analysis).
Protein Length : Ser2-Ser336
Endotoxin : < 0.1 EU/μg of the protein by the LAL method.
Purity : >98% as determined by SDS-PAGE analysis.
Storage : This product is stable after storage at:
-20 centigrade for 12 months in lyophilized state from date of receipt.
-20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping : The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.
Gene Name : LGALS12 lectin, galactoside-binding, soluble, 12 [ Homo sapiens (human) ]
Official Symbol : LGALS12
Synonyms : LGALS12; lectin, galactoside-binding, soluble, 12; galectin-12; galectin 12; GRIP1; galectin-related inhibitor of proliferation; GAL12;
Gene ID : 85329
mRNA Refseq : NM_001142535
Protein Refseq : NP_001136007
MIM : 606096
UniProt ID : Q96DT0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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