Recombinant Human LGALS12 Protein (Ser2-Ser336), N-His tagged, Animal-free, Carrier-free

• Cat.No.: LGALS12-301H
• Product Overview: Recombinant Human LGALS12 Protein (Ser2-Ser336) with N-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Ser2-Ser336
• Description: Galectin-12 (Gal-12) is a lectin family member and is one of the tandem repeat-type galectins containing two carbohydrate recognition domains (CRD) connected by a linker region in a single peptide chain. The CRD is responsible for β-galactoside binding and is required to interact with the VPS13C protein. It has been reported that galectin-12 is presented in the adipose tissue but also expressed in macrophages and other leukocytes. Galectin-12 participates in many biological activities including cell cycle regulation, apoptosis, and cell differentiation. Moreover, galectin-12 has emerged as a crucial factor in driving the macrophage to M1 polarization, leading to inflammation and reducing insulin sensitivity in adipocytes.
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 38.4 kDa.
  The protein migrates as 38 kDa under reducing condition (SDS-PAGE analysis).
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: LGALS12 lectin, galactoside-binding, soluble, 12 [ Homo sapiens (human) ]
• Official Symbol: LGALS12
• Synonyms: LGALS12; lectin, galactoside-binding, soluble, 12; galectin-12; galectin 12; GRIP1; galectin-related inhibitor of proliferation; GAL12
• Gene ID: 85329
• mRNA Refseq: NM_001142535
• Protein Refseq: NP_001136007
• MIM: 606096
• UniProt ID: Q96DT0