Recombinant Human LGMN Protein
Cat.No. : | LGMN-01H |
Product Overview : | Recombinant Human LGMN Protein without tag was expressed in Leishmania. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. |
Source : | Leishmania |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 36 kDa |
Purity : | > 90 % (SDS-PAGE) |
Stability : | Shelf Life: 12 months |
Storage : | Store at -20 centigrade. Avoid freeze/thaw cycles. |
Concentration : | 500 μg/mL |
Storage Buffer : | 20 mM citric acid pH 4.0, 100 mM NaCl, 2 mM DTT |
Shipping : | Gel packs |
Gene Name : | LGMN legumain [ Homo sapiens (human) ] |
Official Symbol : | LGMN |
Synonyms : | LGMN; legumain; AEP; LGMN1; PRSC1; legumain; asparaginyl endopeptidase; cysteine protease 1; protease, cysteine 1; protease, cysteine, 1 (legumain); EC 3.4.22.34 |
Gene ID : | 5641 |
mRNA Refseq : | NM_005606 |
Protein Refseq : | NP_005597 |
MIM : | 602620 |
UniProt ID : | Q99538 |
Products Types
◆ Recombinant Protein | ||
LGMN-3050R | Recombinant Rat LGMN Protein, His (Fc)-Avi-tagged | +Inquiry |
LGMN-2160M | Recombinant Mouse LGMN Protein (18-325 aa), His-tagged | +Inquiry |
LGMN-3353H | Recombinant Human LGMN Protein, His (Fc)-Avi-tagged | +Inquiry |
Lgmn-3778M | Recombinant Mouse Lgmn Protein, Myc/DDK-tagged | +Inquiry |
LGMN-2549C | Recombinant Cynomolgus Monkey LGMN Protein (18-323 aa), His-Myc-tagged | +Inquiry |
◆ Lysates | ||
LGMN-2893MCL | Recombinant Mouse LGMN cell lysate | +Inquiry |
LGMN-001SCL | Recombinant Sus scrofa (Pig) LGMN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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