"LGR6" Related Products

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Recombinant Human LGR6 Protein, Fc-tagged

Cat.No.: LGR6-26H
Product Overview: Recombinant human LGR6 (Ala25-Ala567) protein fused with the Fc region of human IgG1 (Pro100-Lys330) at the C-terminus was expressed in Chinese Hamster Ovary cell line.
Description: This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants.
Source: CHO
Species: Human
Tag : Fc
Predicted N Terminal: Ala25
Bio-activity: Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 2.5-12.5 μg/mL in the presence of 10 ng/mL Recombinant Mouse Wnt‑3a.
Molecular Mass: 87 kDa
Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
Purity: >80%, by SDS-PAGE with silver staining.
Storage: Avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution: Reconstitute at 100 μg/mL in PBS.
Gene Name: LGR6
Official Symbol: LGR6 leucine rich repeat containing G protein-coupled receptor 6 [ Homo sapiens (human) ]
Synonyms: GPCR; VTS20631; FLJ14471; gonadotropin receptor; GPCR; leucine-rich repeat containing G protein-coupled receptor 6; leucine-rich repeat-containing G protein-coupled receptor 6; leucine-rich repeat-containing G-protein coupled receptor 6; Lgr6; LGR6 leucine rich repeat containing G protein-coupled receptor 6
Gene ID: 59352
mRNA Refseq: NM_021636
Protein Refseq: NP_067649
MIM: 606653
UniProt ID: Q9HBX8

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