Recombinant Human LIG1 cell lysate

• Cat.No.: LIG1-985HCL

Specification

• Species: Human
• Tag: Non
• Description: LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: LIG1 ligase I, DNA, ATP-dependent [ Homo sapiens ]
• Official Symbol: LIG1
• Synonyms: LIG1; ligase I, DNA, ATP-dependent; DNA ligase 1; polydeoxyribonucleotide synthase [ATP] 1; MGC117397; MGC130025
• Gene ID: 3978
• mRNA Refseq: NM_000234
• Protein Refseq: NP_000225
• MIM: 126391
• UniProt ID: P18858
• Chromosome Location: 19q13.2-q13.3
• Pathway: Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem
• Function: ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligase activity; ligase activity; metal ion binding; nucleotide binding