| Description : |
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
112.9 kDa |
| AA Sequence : |
MSLAFKIFFPQTLRALSRKELCLFR KHHWRDVRQFSQWSETDLLHGHPLF LRRKPVLSFQGSHLRSRATYLVFLP GLHVGLCSGPCEMAEQRFCVDYAKR GTAGCKKCKEKIVKGVCRIGKVVPN PFSESGGDMKEWYHIKCMFEKLERA RATTKKIEDLTELEGWEELEDNEKE QITQHIADLSSKAAGTPKKKAVVQA KLTTTGQVTSPVKGASFVTSTNPRK FSGFSAKPNNSGEAPSSPTPKRSLS SSKCDPRHKDCLLREFRKLCAMVAD NPSYNTKTQIIQDFLRKGSAGDGFH GDVYLTVKLLLPGVIKTVYNLNDKQ IVKLFSRIFNCNPDDMARDLEQGDV SETIRVFFEQSKSFPPAAKSLLTIQ EVDEFLLRLSKLTKEDEQQQALQDI ASRCTANDLKCIIRLIKHDLKMNSG AKHVLDALDPNAYEAFKASRNLQDV VERVLHNAQEVEKEPGQRRALSVQA SLMTPVQPMLAEACKSVEYAMKKCP NGMFSEIKYDGERVQVHKNGDHFSY FSRSLKPVLPHKVAHFKDYIPQAFP GGHSMILDSEVLLIDNKTGKPLPFG TLGVHKKAAFQDANVCLFVFDCIYF NDVSLMDRPLCERRKFLHDNMVEIP NRIMFSEMKRVTKALDLADMITRVI QEGLEGLVLKDVKGTYEPGKRHWLK VKKDYLNEGAMADTADLVVLGAFYG QGSKGGMMSIFLMGCYDPGSQKWCT VTKCAGGHDDATLARLQNELDMVKI SKDPSKIPSWLKVNKIYYPDFIVPD PKKAAVWEITGAEFSKSEAHTADGI SIRFPRCTRIRDDKDWKSATNLPQL KELYQLSKEKADFTVVAGDEGSSTT GGSSEENKGPSGSAVSRKAPSKPSA STKKAEGKLSNSNSKDGNMQTAKPS AMKVGEKLATKSSPVKVGEKRKAAD ETLCQTKVLLDIFTGVRLYLPPSTP DFSRLRRYFVAFDGDLVQEFDMTSA THVLGSRDKNPAAQQVSPEWIWACI RKRRLVAPCTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
