Recombinant Human LILRB1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | LILRB1-5052H |
Product Overview : | LILRB1 MS Standard C13 and N15-labeled recombinant protein (NP_006660) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Molecular Mass : | 70.8 kDa |
AA Sequence : | MTPILTVLICLGLSLGPRTHVQAGH LPKPTLWAEPGSVITQGSPVTLRCQ GGQETQEYRLYREKKTAPWITRIPQ ELVKKGQFPIPSITWEHAGRYRCYY GSDTAGRSESSDPLELVVTGAYIKP TLSAQPSPVVNSGGNVTLQCDSQVA FDGFILCKEGEDEHPQCLNSQPHAR GSSRAIFSVGPVSPSRRWWYRCYAY DSNSPYEWSLPSDLLELLVLGVSKK PSLSVQPGPIVAPEETLTLQCGSDA GYNRFVLYKDGERDFLQLAGAQPQA GLSQANFTLGPVSRSYGGQYRCYGA HNLSSEWSAPSDPLDILIAGQFYDR VSLSVQPGPTVASGENVTLLCQSQG WMQTFLLTKEGAADDPWRLRSTYQS QKYQAEFPMGPVTSAHAGTYRCYGS QSSKPYLLTHPSDPLELVVSGPSGG PSSPTTGPTSTSGPEDQPLTPTGSD PQSGLGRHLGVVIGILVAVILLLLL LLLLFLILRHRRQGKHWTSTQRKAD FQHPAGAVGPEPTDRGLQWRSSPAA DAQEENLYAAVKHTQPEDGVEMDTR SPHDEDPQAVTYAEVKHSRPRREMA SPPSPLSGEFLDTKDRQAEEDRQMD TEAAASEAPQDVTYAQLHSLTLRRK ATEPPPSQEGPSPAVPSIYATLAIH TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | LILRB1 leukocyte immunoglobulin like receptor B1 [ Homo sapiens (human) ] |
Official Symbol : | LILRB1 |
Synonyms : | LILRB1; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; leukocyte immunoglobulin-like receptor subfamily B member 1; CD85; CD85j; ILT2; LIR 1; LIR1; MIR 7; ILT-2; CD85 antigen; Ig-like transcript 2; leukocyte Ig-like receptor-1; immunoglobulin-like transcript 2; CD85 antigen-like family member J; leukocyte immunoglobulin-like receptor 1; monocyte/macrophage immunoglobulin-like receptor 7; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; MIR7; CD85J; LIR-1; MIR-7; FLJ37515; |
Gene ID : | 10859 |
mRNA Refseq : | NM_006669 |
Protein Refseq : | NP_006660 |
MIM : | 604811 |
UniProt ID : | Q8NHL6 |
Products Types
◆ Recombinant Protein | ||
LILRB1-087H | Recombinant Human LILRB1 protein, His-Avi-tagged | +Inquiry |
LILRB1-646H | Recombinant Human LILRB1 Protein, MYC/DDK-tagged | +Inquiry |
LILRB1-086H | Recombinant Human LILRB1 protein, hFc-tagged | +Inquiry |
LILRB1-1722R | Recombinant Rhesus macaque LILRB1 protein, His-tagged | +Inquiry |
LILRB1-087HB | Recombinant Human LILRB1 protein, His-Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
LILRB1-774HCL | Recombinant Human LILRB1 cell lysate | +Inquiry |
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