Recombinant Human LILRB3 protein, His-Avi-tagged

• Cat.No.: LILRB3-522H
• Product Overview: Recombinant Human LILRB3 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Gly24-Glu443.

Specification

• Description: Leukocyte immunoglobulin-like receptor subfamily B (LILRB3), also known as ILT5, LIR3, and CD85a, is an immunoglobulin superfamily member that is involved in immune regulation. Subfamily B members have cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that inhibit signaling events via phosphatase SHP-1.LILRB3 may act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the Bcell receptor.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 50 KDa. Due to glycosylation, the protein migrates to 60-72 KDa based on Bis-Tris PAGE result.
• Protein length: Gly24-Glu443
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: LILRB3 leukocyte immunoglobulin like receptor B3 [ Homo sapiens (human) ]
• Official Symbol: LILRB3
• Synonyms: CD85 antigen-like family member A; CD85a antigen; CD85a; HL9Immunoglobulin-like transcript 5; ILT5; ILT-5; ILT5CD85a; Leukocyte immunoglobulin-like receptor 3; leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LILRB3; LIR3; LIR3CD85A; LIR-3MGC138403; member 3; Monocyte inhibitory receptor HL9; PIRB
• Gene ID: 1025
• mRNA Refseq: NM_001081450.3
• Protein Refseq: NP_001074919.2
• MIM: 604820
• UniProt ID: O75022