Recombinant Human Low Density Lipoprotein Receptor Adaptor Protein 1, His-tagged
Cat.No. : | LDLRAP1-1396H |
Product Overview : | Recombinant human LDLRAP1 protein, fused to His-tag atN-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | LDLRAP1-1396H | ||
Description : | LDLRAP1(Low density lipoprotein receptor adapter protein 1) is a cytosolic proteinwhich contains a phosphotyrosine binding (PTD) domain. LDLRAP1 is a cytosolic adaptor that couples LDLR to endocyticmachinery. Defects in LDLRAP1are the cause of autosomal recessive hypercholesterolemia (ARH). ARH is adisorder caused by defective internalization of LDL receptors (LDLR) in theliver. | ||
Form : | Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl. | ||
Molecular Weight : | 36.1 kDa (328aa), confirmed by MALDI-TOF. | ||
Purity : | > 90%by SDS-PAGE | ||
Concentration : | 0.5mg/ml(determined by Bradford assay) | ||
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MDALKSAGRA LIRSPSLAKQ SWGGGGRHRK LPENWTDTRE TLLEGMLFSLKYLGMTLVEQ PKGEELSAAA IKRIVATAKA SGKKLQKVTL KVSPRGIILT DNLTNQLIEN VSIYRISYCTADKMHDKVFA YIAQSQHNQS LECHAFLCTK RKMAQAVTLT VAQAFKVAFE FWQVSKEEKE KRDKASQEGGDVLGARQDCT PPLKSLVATG NLLDLEETAK APLSTVSANT TNMDEVPRPQ ALSGSSVVWE LDDGLDEAFSRLAQSRTNPQ VLDTGLTAQD MHYAQCLSPV DWDKPDSSGT EQDDLFSF | ||
Storage : | Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. | ||
OfficialSymbol : | LDLRAP1 | ||
nullValue_other : |
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Gene Name : | LDLRAP1 low density lipoproteinreceptor adaptor protein 1 [ Homo sapiens ] |
Synonyms : | LDLRAP1; low densitylipoprotein receptor adaptor protein 1; ARH; ARH1; ARH2;FHCB1; FHCB2; MGC34705; DKFZp586D0624; OTTHUMP00000008526; LDL receptoradaptor protein; autosomal recessive hypercholesterolemia protein; Lowdensity lipoprotein receptor adaptor protein 1; Autosomal recessivehypercholesterolemia protein |
Gene ID : | 26119 |
mRNA Refseq : | NM_015627 |
Protein Refseq : | NP_056442 |
MIM : | 605747 |
UniProt ID : | Q5SW96 |
Chromosome Location : | 1p36-p35 |
Products Types
◆ Recombinant Protein | ||
LDLRAP1-5026M | Recombinant Mouse LDLRAP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ldlrap1-005M | Recombinant Mouse Ldlrap1 Protein, MYC/DDK-tagged | +Inquiry |
LDLRAP1-9029M | Recombinant Mouse LDLRAP1 Protein | +Inquiry |
LDLRAP1-301431H | Recombinant Human LDLRAP1 protein, GST-tagged | +Inquiry |
Ldlrap1-7874M | Recombinant Mouse Ldlrap1 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
LDLRAP1-4784HCL | Recombinant Human LDLRAP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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