Recombinant Human LOXL1 Protein, GST-tagged

• Cat.No.: LOXL1-4732H
• Product Overview: Human LOXL1 full-length ORF (BAG36895.1, 1 a.a. - 574 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 89.54 kDa
• AA Sequence: MALARGSRQLGALVWGACLCVLVHG QQAQPGQGSDPARWRQLIQWENNGQ VYSLLNSGSEYVPAGPQRSESSSRV LLAGAPQAQQRRSHGSPRRRQAPSL PLPGRVGSDTVRGQARHPFGFGQVP DNWREVAVGDSTGMARARTSVSQQR HGDSASSVSASAFASTYRQQPSYPQ QFPYPQAPFVSQYENYDPASRTYDQ GFVYYRPAGGGVGAGAAAVASAGVI YPYQPRARYEEYGGGEELPEYPPQG FYPAPERPYVPPPPPPPDGLDRRYS HSLYSEGTPGFEQAYPDPGPEAAQA HGGDPRLGWYPPYANPPPEAYGPPR ALEPPYLPVRSSDTPPPGGERNGAQ QGRLSVGSVYRPNQNGRGLPDLVPD PNYVQASTYVQRAHLYSLRCAAEEK CLASTAYAPEATDYDVRVLLRFPQR VKNQGTADFLPNRPRHTWEWHSCHQ HYHSMDEFSHYDLLDAATGKKVAEG HKASFCLEDSTCDFGNLKRYACTSH TQGLSPGCYDTYNADIDCQWIDITD VQPGNYILKVHVNPKYIVLESDFTN NVVRCNIHYTGRYVSATNCKIVQS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LOXL1 lysyl oxidase-like 1 [ Homo sapiens ]
• Official Symbol: LOXL1
• Synonyms: LOXL1; lysyl oxidase-like 1; lysyl oxidase homolog 1; LOL; LOXL; lysyl oxidase-like protein 1
• Gene ID: 4016
• mRNA Refseq: NM_005576
• Protein Refseq: NP_005567
• MIM: 153456
• UniProt ID: Q08397