Recombinant Human LOXL4 protein, FLAG-tagged
Cat.No. : | LOXL4-2159H |
Product Overview : | Recombinant Human LOXL4(500–end) fused with FLAG tag at C-terminal was expressed in Insect cells. |
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Description : | This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. |
Source : | Insect cells |
Species : | Human |
Tag : | FLAG |
Form : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol and 3 mM DTT. |
Molecular Mass : | 31 kDa |
Purity : | >20% |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Storage : | >6 months at –80 centigrade. Avoid freeze/thaw cycles. |
Gene Name | LOXL4 lysyl oxidase-like 4 [ Homo sapiens ] |
Official Symbol | LOXL4 |
Synonyms | LOXL4; lysyl oxidase-like 4; lysyl oxidase homolog 4; FLJ21889; LOXC; lysyl oxidase related C; lysyl oxidase-like protein 4; lysyl oxidase-like 4 pseudogene; lysyl oxidase-related protein C; |
Gene ID | 84171 |
mRNA Refseq | NM_032211 |
Protein Refseq | NP_115587 |
MIM | 607318 |
UniProt ID | Q96JB6 |
Chromosome Location | 10q24 |
Function | copper ion binding; metal ion binding; oxidoreductase activity; protein binding; protein-lysine 6-oxidase activity; scavenger receptor activity; |
Not For Human Consumption!
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