Recombinant Human LOXL4 protein, His-tagged LOXL4-2158H

Recombinant Human LOXL4 protein, His-tagged

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Recombinant Human LOXL4 protein, His-tagged

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Cat.No. : LOXL4-2158H
Product Overview : Recombinant Human LOXL4(570-756) fused with His tag at C-terminal was expressed in E. coli.
Description : This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Source : E. coli
Species : Human
Tag : His
Form : 9 mM Na2HPO4/KH2PO4 pH 7.4, 124 mM KCl, 2.4 mM KCl and 10% glycerol
Molecular Mass : 23 kDa
Purity : ≥90%
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Stability : >6 months at –80 centigrade. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).
Concentration : 0.33 mg/ml
Gene Name : LOXL4 lysyl oxidase-like 4 [ Homo sapiens ]
Official Symbol : LOXL4
Synonyms : LOXL4; lysyl oxidase-like 4; lysyl oxidase homolog 4; FLJ21889; LOXC; lysyl oxidase related C; lysyl oxidase-like protein 4; lysyl oxidase-like 4 pseudogene; lysyl oxidase-related protein C;
Gene ID : 84171
mRNA Refseq : NM_032211
Protein Refseq : NP_115587
MIM : 607318
UniProt ID : Q96JB6
Chromosome Location : 10q24
Function : copper ion binding; metal ion binding; oxidoreductase activity; protein binding; protein-lysine 6-oxidase activity; scavenger receptor activity;

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