Recombinant Human LOXL4 protein, His-tagged


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Recombinant Human LOXL4 protein, His-tagged

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Cat.No. : LOXL4-2158H
Product Overview : Recombinant Human LOXL4(570-756) fused with His tag at C-terminal was expressed in E. coli.
Description : This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Source : E. coli
Species : Human
Tag : His
Form : 9 mM Na2HPO4/KH2PO4 pH 7.4, 124 mM KCl, 2.4 mM KCl and 10% glycerol
Molecular Mass : 23 kDa
Purity : ≥90%
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Stability : >6 months at –80 centigrade. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).
Concentration : 0.33 mg/ml
Gene Name : LOXL4 lysyl oxidase-like 4 [ Homo sapiens ]
Official Symbol : LOXL4
Synonyms : LOXL4; lysyl oxidase-like 4; lysyl oxidase homolog 4; FLJ21889; LOXC; lysyl oxidase related C; lysyl oxidase-like protein 4; lysyl oxidase-like 4 pseudogene; lysyl oxidase-related protein C;
Gene ID : 84171
mRNA Refseq : NM_032211
Protein Refseq : NP_115587
MIM : 607318
UniProt ID : Q96JB6
Chromosome Location : 10q24
Function : copper ion binding; metal ion binding; oxidoreductase activity; protein binding; protein-lysine 6-oxidase activity; scavenger receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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