"LOXL4" Related Products


Recombinant Human LOXL4 protein, His-tagged

Cat.No.: LOXL4-2158H
Product Overview: Recombinant Human LOXL4(570-756) fused with His tag at C-terminal was expressed in E. coli.
Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Source: E. coli
Species: Human
Tag: His
Form: 9 mM Na2HPO4/KH2PO4 pH 7.4, 124 mM KCl, 2.4 mM KCl and 10% glycerol
Molecular Mass: 23 kDa
Purity: ≥90%
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Stability: >6 months at –80 centigrade. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).
Concentration: 0.33 mg/ml
Gene Name: LOXL4 lysyl oxidase-like 4 [ Homo sapiens ]
Official Symbol: LOXL4
Synonyms: LOXL4; lysyl oxidase-like 4; lysyl oxidase homolog 4; FLJ21889; LOXC; lysyl oxidase related C; lysyl oxidase-like protein 4; lysyl oxidase-like 4 pseudogene; lysyl oxidase-related protein C;
Gene ID: 84171
mRNA Refseq: NM_032211
Protein Refseq: NP_115587
MIM: 607318
UniProt ID: Q96JB6
Chromosome Location: 10q24
Function: copper ion binding; metal ion binding; oxidoreductase activity; protein binding; protein-lysine 6-oxidase activity; scavenger receptor activity;

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