| Description : |
This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
94.2 kDa |
| AA Sequence : |
MIPVTELRYFADTQPAYRILKPWWD VFTDYISIVMLMIAVFGGTLQVTQD KMICLPCKWVTKDSCNDSFRGWAAP GPEPTYPNSTILPTPDTGPTGIKYD LDRHQYNYVDAVCYENRLHWFAKYF PYLVLLHTLIFLACSNFWFKFPRTS SKLEHFVSILLKCFDSPWTTRALSE TVVEESDPKPAFSKMNGSMDKKSST VSEDVEATVPMLQRTKSRIEQGIVD RSETGVLDKKEGEQAKALFEKVKKF RTHVEEGDIVYRLYMRQTIIKVIKF ILIICYTVYYVHNIKFDVDCTVDIE SLTGYRTYRCAHPLATLFKILASFY ISLVIFYGLICMYTLWWMLRRSLKK YSFESIREESSYSDIPDVKNDFAFM LHLIDQYDPLYSKRFAVFLSEVSEN KLRQLNLNNEWTLDKLRQRLTKNAQ DKLELHLFMLSGIPDTVFDLVELEV LKLELIPDVTIPPSIAQLTGLKELW LYHTAAKIEAPALAFLRENLRALHI KFTDIKEIPLWIYSLKTLEELHLTG NLSAENNRYIVIDGLRELKRLKVLR LKSNLSKLPQVVTDVGVHLQKLSIN NEGTKLIVLNSLKKMANLTELELIR CDLERIPHSIFSLHNLQEIDLKDNN LKTIEEIISFQHLHRLTCLKLWYNH IAYIPIQIGNLTNLERLYLNRNKIE KIPTQLFYCRKLRYLDLSHNNLTFL PADIGLLQNLQNLAITANRIETLPP ELFQCRKLRALHLGNNVLQSLPSRV GELTNLTQIELRGNRLECLPVELGE CPLLKRSGLVVEEDLFNTLPPEVKE RLWRADKEQATRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
