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Recombinant Human LRRFIP2 Protein, GST-tagged

Cat.No. : LRRFIP2-4641H
Product Overview : Human LRRFIP2 full-length ORF ( NP_060194.1, 1 a.a. - 400 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 71.8 kDa
AA Sequence : MGTPASGRKRTPVKDRFSAEDEALS NIAREAEARLAAKRAARAEARDIRM RELERQQKELDEKSDKQYAENYTRP SSRNSASATTPLSGNSSRRGSGDTS SLIDPDTSLSELRESLSEVEEKYKK AMVSNAQLDNEKNNLIYQVDTLKDV IEEQEEQMAEFYRENEEKSKELERQ KHMCSVLQHKMEELKEGLRQRDELI EKHGLVIIPDGTPNGDVSHEPVAGA ITVVSQEAAQVLESAGEGPLDVRLR KLAGEKEELLSQIRKLKLQLEEERQ KCSRNDGTVGDLAGLQNGSDLQFIE MQRDANRQISEYKFKLSKAEQDITT LEQSISRLEGQVLRYKTAAENAEKV EDELKAEKRKLQRELRTALDKIEEM EMTNSHLAKRLEKMKANRTALLAQQ
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 [ Homo sapiens ]
Official Symbol : LRRFIP2
Synonyms : LRRFIP2; leucine rich repeat (in FLII) interacting protein 2; leucine-rich repeat flightless-interacting protein 2; HUFI 2; LRR FLII-interacting protein 2; HUFI-2; FLJ20248; FLJ22683; FLJ58304; DKFZp434H2035;
Gene ID : 9209
mRNA Refseq : NM_001134369
Protein Refseq : NP_001127841
MIM : 614043
UniProt ID : Q9Y608

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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