Recombinant Human LRRFIP2 Protein, MYC/DDK-tagged

• Cat.No.: LRRFIP2-969H
• Product Overview: Recombinant human LRRFIP2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 48.1 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 [ Homo sapiens ]
• Official Symbol: LRRFIP2
• Synonyms: HUFI-2
• Gene ID: 9209
• mRNA Refseq: NM_001134369
• Protein Refseq: NP_001127841
• MIM: 614043
• UniProt ID: Q9Y608