Recombinant Human LRRFIP2 Protein, MYC/DDK-tagged

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Recombinant Human LRRFIP2 Protein, MYC/DDK-tagged

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Cat.No. : LRRFIP2-969H
Product Overview : Recombinant human LRRFIP2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 48.1 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 [ Homo sapiens ]
Official Symbol : LRRFIP2
Synonyms : HUFI-2
Gene ID : 9209
mRNA Refseq : NM_001134369
Protein Refseq : NP_001127841
MIM : 614043
UniProt ID : Q9Y608

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