Recombinant Human LRRFIP2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human LRRFIP2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : LRRFIP2-495H
Product Overview : LRRFIP2 MS Standard C13 and N15-labeled recombinant protein (NP_001127841) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 48.1 kDa
AA Sequence : MGTPASGRKR TPVKDRFSAE DEALSNIARE AEARLAAKRA ARAEARDIRM RELERQQKEL DEKSDKQYAE NYTRPSSRNS ASATTPLSGN SSRRGSGDTS SLIDPDTSLS ELRDIYDLKD QIQDVEGRYM QGLKELKESL SEVEEKYKKA MVSNAQLDNE KNNLIYQVDT LKDVIEEQEE QMAEFYRENE EKSKELERQK HMCSVLQHKM EELKEGLRQR DELIEKHGLV IIPDGTPNGD VSHEPVAGAI TVVSQEAAQV LESAGEGPLD VRLRKLAGEK EELLSQIRKL KLQLEEERQK CSRNDGTVGD LAGLQNGSDL QFIEMQRDAN RQISEYKFKL SKAEQDITTL EQSISRLEGQ VLRYKTAAEN AEKVEDELKA EKRKLQRELR TALDKIEEME MTNSHLAKRL EKMKANRTAL LAQQTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : LRRFIP2 LRR binding FLII interacting protein 2 [ Homo sapiens (human) ]
Official Symbol : LRRFIP2
Synonyms : LRRFIP2; leucine rich repeat (in FLII) interacting protein 2; leucine-rich repeat flightless-interacting protein 2; HUFI 2; LRR FLII-interacting protein 2; HUFI-2; FLJ20248; FLJ22683; FLJ58304; DKFZp434H2035;
Gene ID : 9209
mRNA Refseq : NM_001134369
Protein Refseq : NP_001127841
MIM : 614043
UniProt ID : Q9Y608

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