Recombinant Human LSS Protein (Asp388-Pro549), His tagged

• Cat.No.: LSS-4462H
• Product Overview: Recombinant human LSS (Asp388-Pro549) fused with His tag was expressed in E. coli.

Specification

• Description: Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S) -2, 3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 20.03 kDa
• Protein Length: Asp388-Pro549
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) [ Homo sapiens (human) ]
• Official Symbol: LSS
• Synonyms: LSS; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase); lanosterol synthase; OSC; hOSC; oxidosqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; 2,3-epoxysqualene--lanosterol cyclase; FLJ25486; FLJ35015; FLJ39450; FLJ46393
• Gene ID: 4047
• mRNA Refseq: NM_001001438
• Protein Refseq: NP_001001438
• MIM: 600909
• UniProt ID: P48449