Active Recombinant Human LYNA Protein, His/GST-tagged

• Cat.No.: LYNA-760H
• Product Overview: Human LYN, full length, amino acids M1-P512 (as in NCBI/Protein entry NP_002341.1), N- terminal GST-HIS6 fusion protein with a Thrombin cleavage site, expressed in Sf9 insect cells.

Specification

• Description: This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: Insect cell
• Species: Human
• Tag: His/GST
• Bio-activity: Specific kinase activity (Pi transfer): 94 pmol/µg × min
  ATP-KM: 1.4 µM
• Molecular Mass: 88.47 kDa
• Storage: At -80 centigrade.
  For complete recovery, mix well and spin before use. Product must not be stored in diluted solutions, aliquots below 10µl are not advisable. Avoid repeated freeze-thaw cycles!
• Concentration: 0.222 µg/µl
• Storage Buffer: 50 mM TRIS-HCl pH 8.0, 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20 % glycerol

Gene Information

• Gene Name: LYN LYN proto-oncogene, Src family tyrosine kinase [ Homo sapiens (human) ]
• Official Symbol: LYN
• Synonyms: LYN; LYN proto-oncogene, Src family tyrosine kinase; JTK8; p53Lyn; p56Lyn; tyrosine-protein kinase Lyn; lck/Yes-related novel protein tyrosine kinase; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; EC 2.7.10.2
• Gene ID: 4067
• mRNA Refseq: NM_00235
• Protein Refseq: NP_002341
• MIM: 165120
• UniProt ID: P07948