Recombinant Human LZTFL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human LZTFL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : LZTFL1-4813H
Product Overview : LZTFL1 MS Standard C13 and N15-labeled recombinant protein (NP_065080) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 34.6 kDa
AA Sequence : MAELGLNEHH QNEVINYMRF ARSKRGLRLK TVDSCFQDLK ESRLVEDTFT IDEVSEVLNG LQAVVHSEVE SELINTAYTN VLLLRQLFAQ AEKWYLKLQT DISELENREL LEQVAEFEKA EITSSNKKPI LDVTKPKLAP LNEGGTAELL NKEILRLQEE NEKLKSRLKT IEIQATNALD EKSKLEKALQ DLQLDQGNQK DFIKAQDLSN LENTVAALKS EFQKTLNDKT ENQKSLEENL ATAKHDLLRV QEQLHMAEKE LEKKFQQTAA YRNMKEILTK KNDQIKDLRK RLAQYEPEDT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : LZTFL1 leucine zipper transcription factor-like 1 [ Homo sapiens (human) ]
Official Symbol : LZTFL1
Synonyms : LZTFL1; leucine zipper transcription factor-like 1; leucine zipper transcription factor-like protein 1; FLJ36386;
Gene ID : 54585
mRNA Refseq : NM_020347
Protein Refseq : NP_065080
MIM : 606568
UniProt ID : Q9NQ48

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