Recombinant Human LZTS1 Protein, GST-tagged

• Cat.No.: LZTS1-4522H
• Product Overview: Human LZTS1 partial ORF ( NP_066300, 514 a.a. - 596 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq, Nov 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 34.87 kDa
• AA Sequence: ERQGHDQMSSGFQHERLVWKEEKEK VIQYQKQLQQSYVAMYQRNQRLEKA LQQLARGDSAGEPLEVDLEGADIPY EDIIATEI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LZTS1 leucine zipper, putative tumor suppressor 1 [ Homo sapiens ]
• Official Symbol: LZTS1
• Synonyms: LZTS1; leucine zipper, putative tumor suppressor 1; F37/Esophageal cancer related gene coding leucine zipper motif; leucine zipper putative tumor suppressor 1; FEZ1; F37/Esophageal cancer-related gene-coding leucine-zipper motif; F37
• Gene ID: 11178
• mRNA Refseq: NM_021020
• Protein Refseq: NP_066300
• MIM: 606551
• UniProt ID: Q9Y250