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Recombinant Human LZTS2 Protein, GST-tagged

Cat.No. : LZTS2-4521H
Product Overview : Human LZTS2 full-length ORF ( NP_115805.1, 1 a.a. - 669 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 99.2 kDa
AA Sequence : MAIVQTLPVPLEPAPEAATAPQAPV MGSVSSLISGRPCPGGPAPPRHHGP PGPTFFRQQDGLLRGGYEAQEPLCP AVPPRKAVPVTSFTYINEDFRTESP PSPSSDVEDAREQRAHNAHLRGPPP KLIPVSGKLEKNMEKILIRPTAFKP VLPKPRGAPSLPSFMGPRATGLSGS QGSLTQLFGGPASSSSSSSSSSAAD KPLAFSGWASGCPSGTLSDSGRNSL SSLPTYSTGGAEPTTSSPGGHLPSH GSGRGALPGPARGVPTGPSHSDSGR SSSSKSTGSLGGRVAGGLLGSGTRA SPDSSSCGERSPPPPPPPPSDEALL HCVLEGKLRDREAELQQLRDSLDEN EATMCQAYEERQRHWQREREALRED CAAQAQRAQRAQQLLQLQVFQLQQE KRQLQDDFAQLLQEREQLERRCATL EREQRELGPRLEETKWEVCQKSGEI SLLKQQLKESQAELVQKGSELVALR VALREARATLRVSEGRARGLQEAAR ARELELEACSQELQRHRQEAEQLRE KAGQLDAEAAGLREPPVPPATADPF LLAESDEAKVQRAAAGVGGSLRAQV ERLRVELQRERRRGEEQRDSFEGER LAWQAEKEQVIRYQKQLQHNYIQMY RRNRQLEQELQQLSLELEARELADL GLAEQAPCICLEEITATEI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : LZTS2 leucine zipper tumor suppressor 2 [ Homo sapiens (human) ]
Official Symbol : LZTS2
Synonyms : LZTS2; leucine zipper tumor suppressor 2; LAPSER1; leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; protein LAPSER1
Gene ID : https://www.ncbi.nlm.nih.gov/gene/?term=84445
mRNA Refseq : NM_001318099
Protein Refseq : NP_001305028
MIM : 610454
UniProt ID : Q9BRK4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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