| Species : |
Human |
| Source : |
E.coli |
| Tag : |
GST |
| Protein Length : |
Ile109-Leu369 |
| Description : |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Form : |
Lyophilized powder/frozen liquid |
| Molecular Mass : |
54.59 kDa |
| Purity : |
>90% as determined by SDS-PAGE. |
| Notes : |
For research use only. |
| Storage : |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
| Storage Buffer : |
0.01M PBS, pH 7.4, 0.02% NLS |
| Reconstitution : |
Reconstitute in sterile water for a stock solution. |
| Shipping : |
They are shipped out with dry ice/blue ice unless customers require otherwise. |
