Recombinant Human MAG Protein, His-tagged

• Cat.No.: MAG-179H
• Product Overview: Recombinant Human MAG, transcript variant 1, fused with His tag at C-terminal was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH7.2
• Molecular Mass: 55.7kD
• AA Sequence: GHWGAWMPSSISAFEGTCVSIPCRF DFPDELRPAVVHGVWYFNSPYPKNY PPVVFKSRTQVVHESFQGRSRLLGD LGLRNCTLLLSNVSPELGGKYYFRG DLGGYNQYTFSEHSVLDIVNTPNIV VPPEVVAGTEVEVSCMVPDNCPELR PELSWLGHEGLGEPAVLGRLREDEG TWVQVSLLHFVPTREANGHRLGCQA SFPNTTLQFEGYASMDVKYPPVIVE MNSSVEAIEGSHVSLLCGADSNPPP LLTWMRDGTVLREAVAESLLLELEE VTPAEDGVYACLAENAYGQDNRTVG LSVMYAPWKPTVNGTMVAVEGETVS ILCSTQSNPDPILTIFKEKQILSTV IYESELQLELPAVSPEDDGEYWCVA ENQYGQRATAFNLSVEFAPVLLLES HCAAARDTVQCLCVVKSNPEPSVAF ELPSRNVTVNESEREFVYSERSGLV LTSILTLRGQAQAPPRVICTARNLY GAKSLELPFQGAHRLMWAKIGPVDH HHHHH
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: MAG myelin associated glycoprotein [ Homo sapiens ]
• Official Symbol: MAG
• Synonyms: MAG; myelin associated glycoprotein; GMA; myelin-associated glycoprotein; S MAG; sialic acid binding Ig like lectin 4A; SIGLEC 4A; SIGLEC4A; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A; S-MAG; SIGLEC-4A
• Gene ID: 4099
• mRNA Refseq: NM_002361
• Protein Refseq: NP_002352
• MIM: 159460
• UniProt ID: P20916