| Description : |
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
158.6 kDa |
| AA Sequence : |
MSKSLKKKSHWTSKVHESVIGRNPE GQLGFELKGGAENGQFPYLGEVKPG KVAYESGSKLVSEELLLEVNETPVA GLTIRDVLAVIKHCKDPLRLKCVKQ GGIVDKDLRHYLNLRFQKGSVDHEL QQIIRDNLYLRTVPCTTRPHKEGEV PGVDYIFITVEDFMELEKSGALLES GTYEDNYYGTPKPPAEPAPLLLNVT DQILPGATPSAEGKRKRNKSVSNME KASIEPPEEEEEERPVVNGNGVVVT PESSEHEDKSAGASGEMPSQPYPAP VYSQPEELKEQMDDTKPTKPEDNEE PDPLPDNWEMAYTEKGEVYFIDHNT KTTSWLDPRLAKKAKPPEECKENEL PYGWEKIDDPIYGTYYVDHINRRTQ FENPVLEAKRKLQQHNMPHTELGTK PLQAPGFREKPLFTRDASQLKGTFL STTLKKSNMGFGFTIIGGDEPDEFL QVKSVIPDGPAAQDGKMETGDVIVY INEVCVLGHTHADVVKLFQSVPIGQ SVNLVLCRGYPLPFDPEDPANSMVP PLAIMERPPPVMVNGRHNYETYLEY ISRTSQSVPDITDRPPHSLHSMPTD GQLDGTYPPPVHDDNVSMASSGATQ AELMTLTIVKGAQGFGFTIADSPTG QRVKQILDIQGCPGLCEGDLIVEIN QQNVQNLSHTEVVDILKDCPIGSET SLIIHRGGFFSPWKTPKPIMDRWEN QGSPQTSLSAPAIPQNLPFPPALHR SSFPDSTEAFDPRKPDPYELYEKSR AIYESRQQVPPRTSFRMDSSGPDYK ELDVHLRRMESGFGFRILGGDEPGQ PILIGAVIAMGSADRDGRLHPGDEL VYVDGIPVAGKTHRYVIDLMHHAAR NGQVNLTVRRKVLCGGEPCPENGRS PGSVSTHHSSPRSDYATYTNSNHAA PSSNASPPEGFASHSLQTSDVVIHR KENEGFGFVIISSLNRPESGSTITV PHKIGRIIDGSPADRCAKLKVGDRI LAVNGQSIINMPHADIVKLIKDAGL SVTLRIIPQEELNSPTSAPSSEKQS PMAQQSPLAQQSPLAQPSPATPNSP IAQPAPPQPLQLQGHENSYRSEVKA RQDVKPDIRQPPFTDYRQPPLDYRQ PPGGDYQQPPPLDYRQPPLLDYRQH SPDTRQYPLSDYRQPQDFDYFTVDM EKGAKGFGFSIRGGREYKMDLYVLR LAEDGPAIRNGRMRVGDQIIEINGE STRDMTHARAIELIKSGGRRVRLLL KRGTGQVPEYDEPAPWSSPAAAAPG LPEVGVSLDDGLAPFSPSHPAPPSD PSHQISPGPTWDIKREHDVRKPKEL SACGQKKQRLGEQRERSASPQRAAR PRLEEAPGGQGRPEAGRPASEARAP GLAAADAADAARAGGKEAPRAAAGS ELCRREGPGAAPAFAGPGGGGSGAL EAEGRAGARAGPRPGPRPPGGAPAR KAAVAPGPWKVPGSDKLPSVLKPGA SAASRTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
