Recombinant Human MAP2K5 Protein, GST-tagged

Cat.No. : MAP2K5-001H
Product Overview : Recombinant Human MAP2K5 Protein with a GST tag was expressed in insect cells.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Source : Insect Cells
Species : Human
Tag : GST
Form : Liquid
Molecular Mass : 77.0 kDa
Purity : 70%-90%
Notes : Small volumes of MEK5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Storage : Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Storage Buffer : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Warning : For Research Use Only. Not for use in diagnostic procedures.
Gene Name : MAP2K5 mitogen-activated protein kinase kinase 5 [ Homo sapiens (human) ]
Official Symbol : MAP2K5
Synonyms : MAP2K5; MAPKK5; MKK5; PRKMK5; SAPKK5; SKK5; HsT17454; mitogen-activated protein kinase kinase 5; dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAPK/ERK kinase 5; MAPKK 5; MEK 5; EC
Gene ID : 5607
mRNA Refseq : NM_145160
Protein Refseq : NP_660143
MIM : 602520
UniProt ID : Q13163

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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