Recombinant Human MAP2K7 Protein, GST-tagged

• Cat.No.: MAP2K7-8085H
• Product Overview: Recombinant full-length human MAP2K7 protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Mitogen-activated protein kinase 7 (MKK7 or MEK7) is a dual-specificity protein kinase of the STE7 family. Directly phosphorylates the Thr-Pro-Tyr motif located in the activation loop of JNK1/2 and activate the kinases in response to environmental stress, pro-inflammatory cytokines or developmental cues. The activation of MKK7 is mediated by various MAPKKKs, including mixed lineage protein kinases (MLKs) and MAPK/ERK kinase (MEK) kinase (MEKK1).
• Source: Insect cell
• Species: Human
• Tag: GST
• Molecular Mass: ~78 kDa
• Purity: > 70%
• Applications: Kinase Assay, Western Blot
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/uL
• Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Gene Information

• Gene Name: MAP2K7
• Official Symbol: MAP2K7 mitogen-activated protein kinase kinase 7 [ Homo sapiens (human) ]
• Synonyms: MAP2K7; mitogen-activated protein kinase kinase 7; MEK; MKK7; JNKK2; MEK 7; MAPKK7; PRKMK7; SAPKK4; SAPKK-4; dual specificity mitogen-activated protein kinase kinase 7; JNK-activating kinase 2; MAP kinase kinase 7; MAPK/ERK kinase 7; SAPK kinase 4; c-Jun N-terminal kinase kinase 2; stress-activated protein kinase kinase 4; EC 2.7.12.2
• Gene ID: 5609
• mRNA Refseq: NM_145185
• Protein Refseq: NP_660186
• MIM: 603014
• UniProt ID: O14733