Recombinant Human MAP2K7 Protein, GST-tagged

Cat.No. : MAP2K7-8085H
Product Overview : Recombinant full-length human MAP2K7 protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
  • Specification
  • Gene Information
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Description : Mitogen-activated protein kinase 7 (MKK7 or MEK7) is a dual-specificity protein kinase of the STE7 family. Directly phosphorylates the Thr-Pro-Tyr motif located in the activation loop of JNK1/2 and activate the kinases in response to environmental stress, pro-inflammatory cytokines or developmental cues. The activation of MKK7 is mediated by various MAPKKKs, including mixed lineage protein kinases (MLKs) and MAPK/ERK kinase (MEK) kinase (MEKK1).
Source : Insect cell
Species : Human
Tag : GST
Molecular Mass : ~78 kDa
Purity : > 70%
Applications : Kinase Assay, Western Blot
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 ug/uL
Storage Buffer : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Gene Name : MAP2K7
Official Symbol : MAP2K7 mitogen-activated protein kinase kinase 7 [ Homo sapiens (human) ]
Synonyms : MAP2K7; mitogen-activated protein kinase kinase 7; MEK; MKK7; JNKK2; MEK 7; MAPKK7; PRKMK7; SAPKK4; SAPKK-4; dual specificity mitogen-activated protein kinase kinase 7; JNK-activating kinase 2; MAP kinase kinase 7; MAPK/ERK kinase 7; SAPK kinase 4; c-Jun N-terminal kinase kinase 2; stress-activated protein kinase kinase 4; EC
Gene ID : 5609
mRNA Refseq : NM_145185
Protein Refseq : NP_660186
MIM : 603014
UniProt ID : O14733

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