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Recombinant Human MAPKAPK5 Protein, His-tagged

Cat.No. : MAPKAPK5-642H
Product Overview : Recombinant Human MAPKAPK5, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 53.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 [ Homo sapiens ]
Official Symbol : MAPKAPK5
Synonyms : MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5; MAP kinase-activated protein kinase 5; PRAK; MAPKAPK-5; MAPKAP kinase 5; MAPK-activated protein kinase 5; p38-regulated/activated protein kinase; MK5; MK-5; MAPKAP-K5;
Gene ID : 8550
mRNA Refseq : NM_003668
Protein Refseq : NP_003659
MIM : 606723
UniProt ID : Q8IW41

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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