Active Recombinant Human MASTL Protein, GST-tagged

• Cat.No.: MASTL-156H
• Product Overview: Recombinant Human EGFR MASTL fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: Microtubule associated serine/threonine kinase-like (MASTL) belongs to the MAST family, AGC Ser/Thr protein kinase group. MASTL promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55δ. Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers.
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
• Bio-activity: 18 nmol/min/mg
• Molecular Mass: 150 kDa
• Purity: > 70%
• Applications: Kinase Assay, Western Blot
• Stability: 1 year at -70 centigrade from date of shipment.
• Storage: Store product at –70centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05 ug/ml

Gene Information

• Gene Name: MASTL microtubule associated serine/threonine kinase-like [ Homo sapiens ]
• Official Symbol: MASTL
• Synonyms: MASTL; microtubule associated serine/threonine kinase-like; serine/threonine-protein kinase greatwall; FLJ14813; THC2; greatwall protein kinase; microtubule-associated serine/threonine-protein kinase-like; GW; GWL; hGWL; MAST-L; GREATWALL; RP11-85G18.2
• Gene ID: 84930
• mRNA Refseq: NM_001172303
• Protein Refseq: NP_001165774
• MIM: 608221
• UniProt ID: Q96GX5