Recombinant Human Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase)

• Cat.No.: MMP3-1839H
• Product Overview: Recombinant HumanMMP3 is a 42.8 kDa protein and was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: MMP3 (matrixmetalloproteinase 3), otherwise known as stromelysin-1, is a member of afamily of secreted zinc-dependent endoproteases, which play a role in thedegradation of extracellular matrix (ECM) components, including bothfibrillar and non-fibrillar collagens, laminin, basement membrane glycoproteinand fibronectin.
• Form: Purified recombinantprotein - lyophilized.
• Application: Functional Assays
• Preparation: Purified recombinant MMP-3 expressed in E.coli.
• Molecular Weight: 42.8kD (378 amino acid residues) containing the entire catalytic N-terminal domain and C-terminal domain.
• Purity: > 98% by SDS PAGEand HPLC analysis
• Endotoxin Level: < 1EU/ug
• Concentration: 0.1mg/ml after reconstitution
• Storage: Prior toreconstitution store at +4oC. After reconstitution store at -20oC.Storage in frost-free freezers is not recommended. This product should bestored undiluted. Avoid repeated freezing and thawing as this may denaturethe antibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.

Gene Information

• Gene Name: MMP3 matrix me tallopeptidase 3(stromelysin 1, progelatinase) [ Homo sapiens ]
• Official Symbol: MMP3
• Synonyms: MMP3; matrixmetallopeptidase 3 (stromelysin 1, progelatinase); SL-1; STMY; STR1;CHDS6; MMP-3; STMY1; MGC126102; MGC126103; MGC126104; stromelysin-1;transin-1; Proteoglycanase; OTTHUMP00000045949; matrix metalloproteinase-3;matrix metalloproteinase 3 (stromelysin 1, progelatinase)
• Gene ID: 4314
• mRNA Refseq: NM_002422
• Protein Refseq: NP_002413
• MIM: 185250
• UniProt ID: P08254
• Chromosome Location: 11q22.3
• Pathway: MatrixMetalloproteinases; Rheumatoid arthritis; p75(NTR)-mediated signaling
• Function: calciumion binding; metalloendopeptidase activity; peptidase activity; proteincomplex binding; zinc ion binding