| Description : |
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
66.2 kDa |
| AA Sequence : |
MPVLSEDSGLHETLALLTSQLRPDS NHKEEMGFLRDVFSEKSLSYLMKIH EKLRYYERQSPTPVLHSAVALAEDV MEELQAASVHSDERELLQLLSTPHL RAVLMVHDTVAQKNFDPVLPPLPDN IDEDFDEESVKIVRLVKNKEPLGAT IRRDEHSGAVVVARIMRGGAADRSG LVHVGDELREVNGIAVLHKRPDEIS QILAQSQGSITLKIIPATQEEDRLK ESKVFMRALFHYNPREDRAIPCQEA GLPFQRRQVLEVVSQDDPTWWQAKR VGDTNLRAGLIPSKGFQERRLSYRR AAGTLPSPQSLRKPPYDQPCDKETC DCEGYLKGHYVAGLRRSFRLGCRER LGGSQEGKMSSGAESPELLTYEEVA RYQHQPGERPRLVVLIGSLGARLHE LKQKVVAENPQHFGVAVPHTTRPRK SHEKEGVEYHFVSKQAFEADLHHNK FLEHGEYKENLYGTSLEAIQAVMAK NKVCLVDVEPEALKQLRTSEFKPYI IFVKPAIQEKRKTPPMSPACEDTAA PFDEQQQEMAASAAFIDRHYGHLVD AVLVKEDLQGAYSQLKVVLEKLSKD THWVPVSWVRTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
