Recombinant Human MDFI Protein, GST-tagged

• Cat.No.: MDFI-4504H
• Product Overview: Human MDFI full-length ORF ( NP_005577.1, 1 a.a. - 246 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 51.4 kDa
• AA Sequence: MYQVSGQRPSGCDAPYGAPSAAPGP AQTLSLLPGLEVVTGSTHPAEAAPE EGSLEEAATPMPQGNGPGIPQGLDS TDLDVPTEAVTCQPQGNPLGCTPLL PNDSGHPSELGGTRRAGNGALGGPK AHRKLQTHPSLASQGSKKSKSSSKS TTSQIPLQAQEDCCVHCILSCLFCE FLTLCNIVLDCATCGSCSSEDSCLC CCCCGSGECADCDLPCDLDCGILDA CCESADCLEICMECCGLCFSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MDFI MyoD family inhibitor [ Homo sapiens ]
• Official Symbol: MDFI
• Synonyms: MDFI; MyoD family inhibitor; myoD family inhibitor; I mfa; inhibitor of MyoD family a; myogenic repressor I-mf; I-MF; I-mfa
• Gene ID: 4188
• mRNA Refseq: NM_005586
• Protein Refseq: NP_005577
• MIM: 604971
• UniProt ID: Q99750