Recombinant Human MDFI Protein, GST-tagged

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Recombinant Human MDFI Protein, GST-tagged

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Cat.No. : MDFI-4504H
Product Overview : Human MDFI full-length ORF ( NP_005577.1, 1 a.a. - 246 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 51.4 kDa
AA Sequence : MYQVSGQRPS GCDAPYGAPS AAPGPAQTLS LLPGLEVVTG STHPAEAAPE EGSLEEAATP MPQGNGPGIP QGLDSTDLDV PTEAVTCQPQ GNPLGCTPLL PNDSGHPSEL GGTRRAGNGA LGGPKAHRKL QTHPSLASQG SKKSKSSSKS TTSQIPLQAQ EDCCVHCILS CLFCEFLTLC NIVLDCATCG SCSSEDSCLC CCCCGSGECA DCDLPCDLDC GILDACCESA DCLEICMECC GLCFSS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : MDFI MyoD family inhibitor [ Homo sapiens ]
Official Symbol : MDFI
Synonyms : MDFI; MyoD family inhibitor; myoD family inhibitor; I mfa; inhibitor of MyoD family a; myogenic repressor I-mf; I-MF; I-mfa;
Gene ID : 4188
mRNA Refseq : NM_005586
Protein Refseq : NP_005577
MIM : 604971
UniProt ID : Q99750

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