Recombinant Human ME1 Protein, GST-tagged

• Cat.No.: ME1-745H
• Product Overview: Recombinant Human full length ME1 was expressed in wheat germ with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 88.66 kDa
• AA Sequence: MEPEAPRRRHTHQRGYLLTRNPHLN KDLAFTLEERQQLNIHGLLPPSFNS QEIQVLRVVKNFEHLNSDFDRYLLL MDLQDRNEKLFYRVLTSDIEKFMPI VYTPTVGLACQQYSLVFRKPRGLFI TIHDRGHIASVLNAWPEDVIKAIVV TDGERILGLGDLGCNGMGIPVGKLA LYTACGGMNPQECLPVILDVGTENE ELLKDPLYIGLRQRRVRGSEYDDFL DEFMEAVSSKYGMNCLIQFEDFANV NAFRLLNKYRNQYCTFNDDIQGTAS VAVAGLLAALRITKNKLSDQTILFQ GAGEAALGIAHLIVMALEKEGLPKE KAIKKIWLVDSKGLIVKGRASLTQE KEKFAHEHEEMKNLEAIVQEIKPTA LIGVAAIGGAFSEQILKDMAAFNER PIIFALSNPTSKAECSAEQCYKITK GRAIFASGSPFDPVTLPNGQTLYPG QGNNSYVFPGVALGVVACGLRQITD NIFLTTAEVIAQQVSDKHLEEGRLY PPLNTIRDVSLKIAEKIVKDAYQEK TATVYPEPQNKEAFVRSQMYSTDYD QILPDCYSWPEEVQKIQTKVDQ
• Storage: store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: ME1 malic enzyme 1, NADP(+)-dependent, cytosolic [ Homo sapiens ]
• Official Symbol: ME1
• Synonyms: ME1; malic enzyme 1, NADP(+)-dependent, cytosolic; NADP-dependent malic enzyme; NADP-ME; malate dehydrogenase; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; pyruvic-malic carboxylase; MES; HUMNDME
• Gene ID: 4199
• mRNA Refseq: NM_002395
• Protein Refseq: NP_002386
• MIM: 154250
• UniProt ID: P48163