| Description : |
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
65.44 kDa |
| AA Sequence : |
MLSRLRVVSTTCTLACRHLHIKEKG KPLMLNPRTNKGMAFTLQERQMLGL QGLLPPKIETQDIQALRFHRNLKKM TSPLEKYIYIMGIQERNEKLFYRIL QDDIESLMPIVYTPTVGLACSQYGH IFRRPKGLFISISDRGHVRSIVDNW PENHVKAVVVTDGERILGLGDLGVY GMGIPVGKLCLYTACAGIRPDRCLP VCIDVGTDNIALLKDPFYMGLYQKR DRTQQYDDLIDEFMKAITDRYGRNT LIQFEDFGNHNAFRFLRKYREKYCT FNDDIQGTAAVALAGLLAAQKVISK PISEHKILFLGAGEAALGIANLIVM SMVENGLSEQEAQKKIWMFDKYGLL VKGRKAKIDSYQEPFTHSAPESIPD TFEDAVNILKPSTIIGVAGAGRLFT PDVIRAMASINERPVIFALSNPTAQ AECTAEEAYTLTEGRCLFASGSPFG PVKLTDGRVFTPGQGNNVYIFPGVA LAVILCNTRHISDSVFLEAAKALTS QLTDEELAQGRLYPPLANIQEVSIN IAIKVTEYLYANKMAFRYPEPEDKA KYVKERTWRSEYDSLLPDVYEWPES ASSPPVITETRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
