| Description : |
This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
N-His |
| Molecular Mass : |
The protein has a calculated MW of 69 kDa. |
| Protein Length : |
M1-L615 |
| AA Sequence : |
MHHHHHHENLYFQGMGLKAAQKTLF PLRSIDDVVRLFAAELGREEPDLVL LSLVLGFVEHFLAVNRVIPTNVPEL TFQPSPAPDPPGGLTYFPVADLSII AALYARFTAQIRGAVDLSLYPREGG VSSRELVKKVSDVIWNSLSRSYFKD RAHIQSLFSFITGTKLDSSGVAFAV VGACQALGLRDVHLALSEDHAWVVF GPNGEQTAEVTWHGKGNEDRRGQTV NAGVAERSWLYLKGSYMRCDRKMEV AFMVCAINPSIDLHTDSLELLQLQQ KLLWLLYDLGHLERYPMALGNLADL EELEPTPGRPDPLTLYHKGIASAKT YYRDEHIYPYMYLAGYHCRNRNVRE ALQAWADTATVIQDYNYCREDEEIY KEFFEVANDVIPNLLKEAASLLEAG EERPGEQSQGTQSQGSALQDPECFA HLLRFYDGICKWEEGSPTPVLHVGW ATFLVQSLGRFEGQVRQKVRIVSRE AEAAEAEEPWGEEAREGRRRGPRRE SKPEEPPPPKKPALDKGLGTGQGAV SGPPRKPPGTVAGTARGPEGGSTAQ VPAPTASPPPEGPVLTFQSEKMKGM KELLVATKINSSAIKLQLTAQSQVQ MKKQKVSTPSDYTLSFLKRQRKGL |
| Endotoxin : |
< 0.1 EU/μg by LAL |
| Purity : |
> 90% by SDS-PAGE |
| Storage : |
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : |
0.32 mg/mL by BCA |
| Storage Buffer : |
Sterile 50 mM Tris, 200 mM NaCl, pH7.5, 20% Glycerol |
