Recombinant Human METTL14 Protein (Full Length), N-GST-tagged

• Cat.No.: METTL14-35H
• Product Overview: Recombinant full-length human METTL14 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: N6-adenosine-methyltransferase subunit METTL14 (Methyl-transferase-like protein 14 or METTL14) methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG] GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability.
• Source: Sf9 insect cells
• Species: Human
• Tag: N-GST
• Molecular Mass: ~84 kDa
• Protein Length: Full Length
• Purity: >85%
• Stability: One year at -70 centigrade from date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.5 μg/μL
• Storage Buffer: Recombinant protein stored in 50mM Tris-HCI, pH 7.5, 150mM NaCI, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Shipping: Dry ice.

Gene Information

• Gene Name: METTL14 methyltransferase 14, N6-adenosine-methyltransferase subunit [ Homo sapiens (human) ]
• Official Symbol: METTL16
• Synonyms: METTL14; methyltransferase 14, N6-adenosine-methyltransferase subunit; hMETTL14
• Gene ID: 57721
• mRNA Refseq: NM_020961
• Protein Refseq: NP_066012
• MIM: 616504
• UniProt ID: Q9HCE5