Recombinant Human MILR1 Protein (Met1-Lys227), HIgG1 Fc-tagged

• Cat.No.: MILR1-643H
• Product Overview: Recombinant Human MILR1 Protein (NP_001078892.1) (Met1-Lys227) was produced by HEK293 Cells expression system. This protein was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Description: Cell surface immunoreceptor MILR1 (mast cell immunoglobulin-like receptor 1; synonyms, Allergin-1) has been shown to suppress immunoglobulin E (IgE)-mediated, mast cell-dependent responses in both mice and humans.The C allele of rs65423 was associated with increased expression of MILR1, which was in accordance with the results of expression quantitative trait loci analysis using human leukocytes. The rs65423 polymorphism affects MILR1 expression levels in humans, leading to a susceptibility to producing specific IgE antibodies against common allergens.
• Source: HEK293
• Species: Human
• Tag: HIgG1 Fc
• Predicted N Terminal: Arg 20
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant human MILR1 consists of 446 amino acids and predicts a molecular mass of 50.1 kDa.
• Protein length: Met1-Lys227
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 90 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade.
• Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
  Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Gene Information

• Gene Name: MILR1 mast cell immunoglobulin like receptor 1 [ Homo sapiens (human) ]
• Official Symbol: MILR1
• Synonyms: MCA32; MCA-32; C17orf60; Allergin-1
• Gene ID: 284021
• mRNA Refseq: NM_001085423
• Protein Refseq: NP_001078892
• UniProt ID: Q7Z6M3