Recombinant Human Mineralocorticoid receptor LBD/Hsp90 complex, GST-tagged

• Cat.No.: NR3C2-105H
• Product Overview: GST-tagged Mineralocorticoid receptor ligand-binding domain (MR-LBD) consists of a 218 a.a. GST tag, a 30 a.a. flexible linker and a 381 a.a. MR-LBD, Acc# AAA59571, amino acids 604-984. GST tagged MR-LBD and Hsp90 are the major components of the complex.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Form: 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 7 mM reduced glutathione, 15% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: NR3C2 nuclear receptor subfamily 3, group C, member 2 [ Homo sapiens ]
• Official Symbol: NR3C2
• Synonyms: NR3C2; nuclear receptor subfamily 3, group C, member 2; MLR; mineralocorticoid receptor; MR; aldosterone receptor; mineralocorticoid receptor 1; mineralocorticoid receptor delta; MCR; NR3C2VIT; FLJ41052; MGC133092
• Gene ID: 4306
• mRNA Refseq: NM_000901
• Protein Refseq: NP_000892
• MIM: 600983
• UniProt ID: P08235
• Chromosome Location: 4q31
• Pathway: ACE Inhibitor Pathway, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem
• Function: metal ion binding; protein binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding